Matthew Perry spent final days ‘angry and mean’ after testosterone shots says friend

Matthew Perry spent final days ‘angry and mean’ after testosterone shots says friend

December 18, 2023

Matthew Perry, who was best known for playing the funnyman Chandler Bing in the sitcom Friends, tragically passed away on 28 October this year. The actor was found unresponsive in his jacuzzi at his LA home, before being pronounced dead at just 54 years old.

Recently, the late actor's autopsy report was shared, which confirmed the star had died from the "acute effects of ketamine." It also stated further contributing factors to Matthew's death, which included drowning, coronary artery disease and the effects of buprenorphine. The post-mortem explained that the latter can be "used to treat opioid use disorder."

According to the document, Matthew had been "receiving ketamine infusion therapy for depression and anxiety," but his last dose was reportedly taken one and a half weeks before he died. Therefore, the autopsy revealed that "the ketamine in his system at death could not be from that infusion therapy, since ketamine's half-life is three-to-four hours, or less."

Elsewhere in the autopsy report, it states that a female friend had described Matthew's personality as "angry and mean" in the weeks leading up to his death. Apparently, this was a result of the testosterone shots he had been taking.

Furthermore, it was revealed Matthew had been taking Tamoxifen to help him lose weight, a drug that is typically reserved for breast cancer patients. Plus, anti-diabetic medication and nicotine patches, as he had been trying to quit smoking when he died.

Jennifer Aniston, Matthew's Friends co star confirmed this, sharing that she had been texting him on the morning he passed away. Claiming that he was in a good place, Jennifer said: "He had quit smoking. He was getting in shape. He was happy – that's all I know.

"I was literally texting with him that morning, funny Matty. He was not in pain. He wasn't struggling. He was happy," the 54 year old shared.

It's long been known that Matthew had stuggled with alcohol and painkiller addiction throughout his life. The star most recently divulged all in his celebrated memoir, Friends, Lovers and the Big Terrible Thing, in which he recalled his experiences in a raw, candid, honest and witty manner.

But while promoting the book, Matthew shared that he would rather be remembered for helping others fight addiction than for his career defining role in Friends.

During a podcast chat with host Tom Power – which following Matthew's death is particularly poignant – he said: "The best thing about me, bar none, is that if somebody comes to me and says, 'I can't stop drinking, can you help me?' I can say 'yes' and follow up and do it.

"When I die, I don't want Friends to be the first thing that's mentioned. I want that to be the first thing that's mentioned. And I'm gonna live the rest of my life proving that."

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